Funded Projects

PORTICO has funded the following projects:

Date Awarded Study Name Award Recipient Study Support
03 FEB 2023 Predictors of Medication-Free remission in Juvenile Myositis: an observational pilot study Dr. Ilaria Maccora Statistical support to identify predictors of medication free remission in JDM.
23 JAN 2023 Factors Associated with Medication-Free Remission in Juvenile Dermatomyositis Dr. Shelia Angeles-Han Statistical support to identify predictors of medication free remission in JDM. We will compare clinical variables. Support will enable mentorship, abstract submissions and a publication over the next 6 months for a clinical research coordinator/MD applying for residency. It will also enable submission of foundation grants to The Myositis Association and CureJM.
01 NOV 2022 Phenotypes and functions of neutroophils in the pathogenesis of systemic juvenile idiopathic arthritis Natsumi Inoue, research fellow Support for participant's compensation, and resources for participant's exams and blood collection
07 SEP 2022 Pain, Physical Activity, and Health Robert Gibler, PhD, psychology fellow Data Management support to develop system in REDCap to collect participants' daily reports of pain, mood, and fatigue
07 SEP 2022 RheumsMart Dr. Hermine Brunner Support for mulitple lupus projects with data management
07 SEP 2022 Corticosteroid Dosing Calculator (PLUMM study) Dr. Hermine Brunner Funds given to support NIH grant
17 AUG 2022 Prevalence and Impact of Widespread Pain in Pediatric SLE (pSLE), Lupus Spectrum Disease and Juvenile Dermatomyositis (JDM) Dr. Sara Patrizi, outside investigator at Stanford University Statistical Analysis, with a plan to submit an abstract, and completing and publishing a manuscript
26 JUL 2022 Validation of the Tampa Scale of Kinesiophobia in Youth with Pain Laura E. Simons, PHD Bio statistician/psychometrics support for analyzing the measurement properties Tampa Scale of Kinesiophobia using already collected datasets
19 JUL 2022 LUpus Nephritis and Cellcept precision dosing in cHildren (LaUNCH) Dr. Hermine Brunner Support for the statisticians in the analysis of the steroid dosing regimen data in preparation for upcoming clinical trial.
15 JUL 2022 9-year-old with arthralgia and rash following pituitary adenoma Dr. Katherine Schultz Covered publication costs for case study
15 JUL 2022 Evaluation of the Lupus Low Disease Activity State (LLDAS) vs. the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)-2K Score in a Pediatric Systemic Lupus Erythematosus Cohort Dr. Bridget Wilson Funding for statistical analysis to compare Lupus Low Disease Activity State (LLDAS) and low SLEDAI-status in children with SLE.
11 JUL 2022 Prognostic Factors of Dermatomyositis Associated Outcomes in Children Dr. Sheila Angeles-Han Statistical Analysis to explore the differences in disease course and outcomes in children with JDM, specifically any relationship between the time of remission and treatment regimens
14 JUN 2022 Psychosocial Factors Associated with Knee joint loading in Youth post-ACL Reconstructive Surgery Christin Zwolski, DPT, PhD Pilot and Feasibility award to complete a pilot study of how the psychosocial response to ACLR may impact knee joint loading, with the results expected to inform the design of a future research career development proposal. Ultimately, this research will lead to the development of individualized rehabilitation interventions that may positively influence long-term joint health and movement among youth with musculoskeletal diseases or injuries.
10 MAY 2022 Resilience among Patients with Juvenile Idiopathic Arthritis Dr. Daniella Schocken Assistance with statistical analysis and building REDCap for study questionnaire administration and e-consent
22 MAR 2022 Effect of Corticosteroids on Cerebrovascular Imaging Markers Mark DiFrancesco, PHD Funding support of IRC research associates to perform imaging analyses under direction of the PI.
22 FEB 2022 Musculoskeletal Ultrasound Evaluation in Pediatric Psoriasis Dr. Laura Nedorezov Study design and participant reimbursement for an investigation exploring if pediatric psoriasis patients have signs of subclinical arthritis on MSUS evaluation.
22 DEC 2021 Impact of Corticosteroids on Advanced Imaging Measures and Neurocognitive Testing Dr. Ekemini Ogbu Methods Core faculty support for the statistical analysis of pilot data for a grant application
06 DEC 2021 Lupus Low Disease Activity State (LLDAS) Dr. Ellen Cody, fellow Statistical analysis support of a retrospective study for CCHMC patients diagnosed with SLE to assess the differences between rates of LLDAS and SLEDAI in children
14 OC 2021 Utility of the renal activity index for lupus nephritis (RAIL) in identifying active lupus nephritis Dr. Najla Aljaberi Analysis and interpretation of results for a novel lupus nephritis biomarker and support for publication
22 JUL 2021 Patient-Reported Outcomes in SJIA Chronic Lung Disease Ndate Fall, RN, MSN Assistance in developing and validating a profile of patient reported outcome measures that captures the effects of SJIA-LD on health outcomes.
30 JUN 2021 Effect of Low-Dose Methotrexate on Brain Microstructure Mark DiFrancesco, PHD Pilot and Feasibility Grant award to find neuroimaging biomarkers of the effects of methotrexate treatment in JIA patients with longer-term goals of personalized prediction and avoidance of adverse effects.
30 JUN 2021 Executive Functioning in Juvenile-Onset Fybromyalgia Kristen Jastrowski Mano, PhD Pilot and Feasibility Grant to provide strong pilot data as a foundation for a more definitive R01 level grant application that will evaluate executive functioning (EF) in a large representative sample of JFM patients and study the impact of specific domains of EF disruption on daily functioning.
08 JUN 2021 Presence and Impact of Sleep and Rest-Activity Rhythms in Adolescents with Juvenile-Onset Fibromyalgia (JFM) Christopher D. King, PhD Additional support to create a more full-featured data pipeline for our current actigraphy data collected from adolescents with JFM and the FIT teens Study
10 MAY 2021 Improving outcomes in juvenile idiopathic arthritis (JIA) by co-designing patient-facing online graphic user interface to inform optimal RWD-driven patient-centered treatment strategies Bin Huang, PhD Support in building a patient facing graphic user interface to inform evidence-based treatment effectiveness for children with JIA
23 NOV 2020 JFM and activity avoidance's effect on maladaptive biomechanics Scott Bonnette, PhD Pilot and Feasibility Grant to support work on delineating how fear of movement disrupts the spatiotemporal structure of gait initiation and maintenance in patients with JFM
10 JUN 2020 Biobehavioral Measurement of Outcomes Juvenile-Onset Fibromyalgia Christopher King, PhD Use of data management and statistical resources through PORTICO to assist the development of a functional analysis pipeline to automate the calculation of (a) sleep outcomes and (b) circadian rest/activity rhythms (RAR’s).
23 APR 2020 Validation of a novel ultrasound score for the evaluation of pediatric synovitis Dr. Patricia Vega-Fernandez Covering the costs associated with MRI scans (MRI, nursing coverage, radiology informatics team) to validate a novel Pediatric Arthritis US Scoring system for the assessment of knee arthritis in JIA.
23 APR 2020 Identifying Neural Pathophysiology In Juvenile Fibromyalgia Dr. Robert Coghill Funding for structural and functional MRI scans in order to assess changes in brain activation in patients during pain and multisensory tasks as well as during resting state.
21 APR 2020 Studying Tear Markers in Pediatric uveitis (STOMP) - Uveitis Activity Study Dr. Sheila Angeles-Han Data management support to upgrade existing REDCap database to include data cleaning and report programming. Assistance for statistical support to analyze samples to calculate sample size requirements.
21 APR 2020 Musculoskeletal Ultrasound Study in Childhood Arthritis Limited Examination Dr. Patricia Vega-Fernandez Statistical and methodological support to analyze the data in order to determine minimum number of joints needed to assess at least 90% MSUS-evidenced disease activity in JIA